KIN104 Lecture Notes - Lecture 8: Micronutrient, Polypharmacy, Sarcopenia

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Certain quantity of life at birth: genetics, parental health, fetal health. 90% functionally independent at 20 years old: healthier lifestyles (70%): non obese, non-smokers, adapt to stress, good genes (30%): children after 40, long-lived parents. Common factors: gender, social interaction, positive attitude, cognitive stimulation, diet/non-obese, non-smoking, none to limited alcohol, limit stress. 40-75% of chronic disease related to diet, either leads to or managed by. Osteoporosis, heart disease, stroke, dementia, many cancers: quality diet predicts longevity and quality of life. Normal body weight, moderate alcohol, plant-based mediterranean diet. Low serum vitamin e and d associated with impaired physical functioning: ramesh et al. , 2010. Increased incidence of dementia: high saturated fat, calories and alcohol. Low intake of antioxidants, fish, methionine, vitamins: semba et al. , 2006. Those with lowest protein (0. 7 g/kg/d) at baseline lost 40% more muscle mass than those with highest (1. 1 g/kg) Low levels of serum vitamin d, carotenoids, selenium, zinc, b6, b12 predicted disability.

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