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MICB 202 (46)

Class Notes for MICB 202 at University of British Columbia

Introductory Medical Microbiology and Immunology

Exam Study Guides for MICB 202

Covers all exam topics.

MICB 202 Lecture Notes - Lecture 11: Hybridoma Technology, Antiserum, Cancer Cell
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Topic 7: Antibodies as Tools in Medicine and Biology Antibodies have all sorts of applications. Cancers express particular protein. Epitope = antigenic determinant (where B cells bind to on an antigen) Polyclonal ...

Microbiology
MICB 202
Tracy Kion
MICB 202 Lecture Notes - Lecture 8: Septic Shock, Mast Cell, Anaphylaxis
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Topic 5: Unwanted Immune Responses Symptoms of immune response are caused by unwanted cytokines in the body. Fever – caused by cytokines the act on hypothalamus (determines body temp.); helps APC Localized immune resp...

Microbiology
MICB 202
Tracy Kion
MICB 202 Lecture Notes - Lecture 4: Lymph Node, Immunoglobulin D, Immunoglobulin M
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Topic 4: Immune Response to Pathogens Proteins are a major component of both bacterial and viral pathogens. Sometimes pathogens have different structures on their outermost surface. B cells can make antibodies again...

Microbiology
MICB 202
Tracy Kion
MICB 202 Lecture Notes - Lecture 3: Cytotoxic T Cell, Mhc Class Ii, T Helper Cell
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Topic 3: Components of the Adaptive Immune System All species have their own MHC proteins. T helper cells (TH) are important in all aspect of the adaptive immunity. Killer T cells (CTL) are important in protecting the...

Microbiology
MICB 202
Tracy Kion
MICB 202 Lecture Notes - Lecture 2: Adaptive Immune System, Complement System, Defensin
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Topic 2: Innate Immune Responses Innate response • takes care of the bulk of the infection • controls the infection • very crucial Adaptive response • kicks in after innate response • takes ...

Microbiology
MICB 202
Tracy Kion
MICB 202 Lecture Notes - Lecture 1: Lymphatic Vessel, T Helper Cell, Cytotoxic T Cell
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Topic 1: Introduction to the Immune System We are mostly microbial cells (90%) Neutrophils • make up 65% of WBC most common leukocytes • can increase immune response • life span of ~12 hours Monocyte a...

Microbiology
MICB 202
Tracy Kion
MICB 202 Lecture Notes - Lecture 5: Teichoic Acid, Pie Chart, Gram-Negative Bacteria
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Topic 1: Introduction and Vocabulary Solar viruses in the ocean are very important to nutrient cycling. On the pie chart: infectious diseases and percentage of DALYs accounted for them Tuberculosis​ and ​Pertussis​ are ...

Microbiology
MICB 202
Tracy Kion
MICB 202 Lecture Notes - Lecture 10: Polio Vaccine, Influenza Vaccine, Vp3
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Topic 2: Picornavirus case study (Not active) Capsomers: basic subunit of the capsid (asymmetrical structure) Poliovirus - organised in the way to make a symmetrical (​icosahedron​) shape - Immature form: ...

Microbiology
MICB 202
Tracy Kion
MICB 202 Lecture 9: Aug 1 lecture (Virology Topic 1)
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Topic 1: Introduction to Viruses Molecular diversity, properties, and pathogenicity Around 50 of the human genome (DNA) originates from viral sequences. Viruses are probably the most diverse group of organisms on the plane...

Microbiology
MICB 202
Tracy Kion
MICB 202 Lecture Notes - Lecture 6: Lactoperoxidase, Staphylococcus Epidermidis, Dextran
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Topic 3:Microbiota of Humans, Barriers to Infection and Aspects of Innate Immunity The defense protein targets the PG of the cell way. Lysozyme – adds water to the O-glycosidic linkages (not peptide chains) and causes o...

Microbiology
MICB 202
Tracy Kion
MICB 202 Lecture Notes - Lecture 7: Trp Operon, Siderophore, Genitourinary System
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Topic 4: Pathogenicity and Virulence Mechanisms of Pathogenic Bacteria Virulence – depends on both the pathogen and the host (pathogen-host interaction) Virulence factor: anything a pathogenic bacteria has (either struc...

Microbiology
MICB 202
Tracy Kion
MICB 202 Lecture Notes - Lecture 12: Simian Immunodeficiency Virus, Chemokine Receptor, Reverse Transcriptase
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Topic 4: Retroviruses case study Human Immunodeficiency Virus (HIV) - virus that can lead to AIDS - subgroup Lentiviruses, or “slow” viruses - long interval between initial infection and onset of seri...

Microbiology
MICB 202
Tracy Kion

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