ANP 1107 Lecture Notes - Lecture 16: Urobilin, Inulin, Osmotic Concentration

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1107
• Professor: Jackie Carnegie

Document Summary

Enhancing urinary output diuretics any substance that is not reabsorbed or exceed renal reabsorption ability (i. e glucose) Effect of alcohol on urine formation inhibits release of adh, thus causes dehydration. Caffeine and most prescribed diuretic drugs inhibit sodium reabsorption blood volume will decrease b/c decrease in na+ reabsorption will decrease reabsorption of water. Renal clearance: colume of plasma from which a substance is 100% cleared per unit time: rc = uv/p in ml/min; u = [substance mg/ml ]in urine, v = flow rate of urine formation ml/min, p = If concentration of substance in urine is the same as the gfr (125 ml/min), then the rc = gfr: a rc less than 125 indicates some absorption of the substance. If rc of substance is greater than rc of inulin i. e creatine then. If rc = 0, then all the substance is being absorbed (i. e glucose, amino acids)