ANP 1105 Lecture Notes - Lecture 2: Fibronectin, Elastic Fiber, Macrophage

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1105
• Professor: William Staines

Document Summary

Ground substance: an amorphous gel-like substance surrounding the cells. Contains cell adhesion proteins (fibronectin, laminin) and proteoglycans (water retention). Elastin that has a coiled structure to allow stretch and recoil. Found in the walls of large arteries. Gel-like matrix with all three fiber types. Composed of fibroblasts, macrophages (immune response), mast cells (inflammatory response) and some white blood cells. It"s a reservoir of water and salts and is a prime site of edema (water retention) during inflammatory response. Areolar ct is widely distributed under the epithelium of the body. Cushions all major organs, allows for fast immune and inflammatory responses. Much like areolar ct, but modified to store nutrients. Found under the skin, around kidneys, eyes and inside bone. Acts as a fuel reservoir, insulation, and supports and protects organs. Much like areolar connective tissue, but only contains reticular fibers. Found in lymphoid organs, such as the lymph nodes, bone marrow, and the spleen.