ANP 1107 Lecture Notes - Lecture 9: Thyrotropin-Releasing Hormone, Hyperthyroidism, Myxedema

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1107
• Professor: Jackie Carnegie

Document Summary

Regulation of metabolism and body temperature: hepatic functions associated with metabolism. The liver is one of the most biochemically complex organs in the body and conducts over 500 metabolic functions. Processes nearly every class of nutrients and plays a major role in regulation of plasma cholesterol levels. General metabolic functions: carbohydrate metabolism: isomerize monosaccharides to glucose. Packages glucose as glycogen and fat-serves as a glucose store. Gluconeogenesis: converts amino acids or glycerol to glucose when needed: fat metabolism: Metabolizes cholesterol, bile salts: protein metabolism: principal site of amino acid deamination (forms urea for removal of ammonia) Triglycerides and cholesterol are insoluble in an aqueous environment, and therefore cannot circulate freely in the blood are transported as lipoproteins. All lipoproteins are composed of varying proportions of triglycerides, phospholipids and cholesterol, in addition to protein. Protein important for regulating entry into speci c target cells. In general, the higher the % lipid in a lipoprotein, the lower its density.