ANP 1107 Lecture Notes - Lecture 9: Bile Acid, Adipose Tissue, Lipoprotein

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2. 5 list the various hepatic functions associated with metabolism. The liver one of the most biochemically complex organs in body conducts over 500 metabolic functions. Processes nearly every class of nutrients & plays a major role in regulation of plasma cholesterol levels. 2. 6 list and describe the 4 major types of lipoproteins. Chylomicrons: lowest density; transport newly adsorbed lipids from gi tract. Vldl: primarily made in liver, transports triglycerides to peripheral tissues (mostly adipose tissue, at target cells, the triglycerides are unloaded", vldls become ldl. Ldl: primary role is deliver cholesterol to peripheral tissues. Recall cholesterol is needed for many functions steroid hormones, bile salts, membranes, signaling molecules in development, etc. Excess blood cholesterol (> 200 mg/dl) is linked to an elevated risk of atherosclerosis and associated stroke and heart attack. The form of cholesterol is important in this consideration: Hdl are believed to be good because the cholesterol associated with hdl is mainly destined for degradation.

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