BIO 1140 Lecture Notes - Lecture 15: Small Interfering Rna, Microrna, Rna Interference
28 Mar 2017
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Alp - in eukaryotes, differences in gene expression between various cel types in one individual are best explained by_____. Enhancers are recognized by activators found only in speci c cell types. In addition to tlc; activators and repressors control which genes are expressed and the rate at which transcription occurs. Another level after they leave the nucleus - they don"t all make its. Use mirna (micro rna) that come from spliced introns. Mirna: what the cell produces in terms of what the cell introduces in terms of short interfering rna. Transcription regulation is regulation of transcription initiation. Chromatin remodelling to make genes accessible for transcription. There are variations in pre-mrna processing and rate of mrna breakdown. Determines types and availability of mrnas to ribosomes. Sirna can bind mrna and target to degradation -> no translation. Micro rnas are important for regulation of gene expression. They form mrrisc - halts translation and or reduces available mrna.
