BIO 2133 Lecture Notes - Lecture 12: Blind Fish, Hearing Loss, Epistasis

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Incomplete dominance is where both genes are expressed as a mix, incompletely fulfilling neither gene. Both genes are being expressed fully so you get a bunch of splotches of both genes being expressed. One gene product that masks the effects of another gene phenotype. First, the s2 would be expressed, but gets masked by the s3. Steps of pathway are dependant on each other. In drosophila, red and yellow eye pigments are synthesized through the pterin pathway. A part of the pterin pathway (simplified) is shown below. E1 is recessively epistatic to e2 and e3. Recessively epistatic = reaction of e2 and e3 based on e1. Brown is the second enzyme then black if dominant. It is b, for the most purple flowers. Deafness, two hearing people can make deaf kids. When two deaf people make a baby, their kids generally can hear. Deafness is a combination of two genes, a and b.

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