BIO 3153 Lecture Notes - Lecture 19: Calmodulin 1, Calmodulin, Calcium Signaling
Document Summary
3 types we"ve looked at: depolarizaitoninduced ca2+ release. These processes are important for muscle contraction, secretion from vesicles, other intercellular mechanisms. Activation of plasma membrane ca2+ channels induces influx. If it was a neuron, depolarization could be from influx of na+ They"re named like this because of their pharmacological characterization. Calcium will bind to these receptors which will release more calcium into the. Er or sr, which will lead to more calcium coming out. In the retina, this is an important mechanism. Low cytosolic ca2+ is otherwise maintained by ca2+ pump. Calcium is always kept in low concentrations, because otherwise there would be a flooding of signals. Calcium is released and eventually there is a slight increase in intercellular calcium which could result in activation of something (ex. Always more calcium inside the er and outside the cell than there is in the cytosol.
