BIO 3102 Lecture Notes - Lecture 15: Frameshift Mutation, Lactose Intolerance, Myocyte
7 Apr 2017
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Document Summary
Applications of molecular phylogenetics: archaeology/ paleontology (ancient dna analysis, conservation bio. Power of and pitfalls of pcr (pcr: rapid amplification of specific genomic regions using very small amount of dna, damaged dna can lead to sequence artifacts, ancient dna can be contaminated with modern dna. Otzi the iceman: 5300 year old frozen mummy from italian alps found in 1991, the research helps flesh out a picture of the iceman, who had brown hair, type o blood, lactose intolerance common among neolithic agrarian societies. Lineage to modern humans = from africa: migration out of africa = diff population, many molecular studies support out of africa hypothesis. The y chromosome data also supports this migration hypothesis: the y-mrca through the male lineages. Just noticing the presence of the y and the mitochondrial sequences. Long branches attract phenomenon: can get homoplasies that occur more frequent than by chance, panel b = parallel subs true tree.
