BPS 1101 Lecture Notes - Lecture 12: Sulfanilamide, Animal Testing, Lipid Bilayer

18 views4 pages

Document Summary

Drugs must pass through many barriers before reaching the target, and some is lost as it passes through each one. Most drugs pass through the digestive tract. 1st barrier is the stomach: drug must resist acid & dissolve in water. 2nd barrier is the small intestine: drug must resist digestive enzymes. This is where most drugs are absorbed through diffusion. The drug must be able to pass through the lipid membrane. It is very difficult to make a drug soluble in both. 3rd barrier is the liver: modifies the drugs, so they must be resistant to this. Designing a drug that can pass through all these barriers is the hardest part of med. Must bond to the biological factors when they reach the target. So they must be present in sufficient concentrations. When the drug binds to the desired target the desired effect is produced. Side effects are undesired effects, but not necessarily harmful (ex. sleepiness)

Get access

Grade+20% off
$8 USD/m$10 USD/m
Billed $96 USD annually
Grade+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
40 Verified Answers
Class+
$8 USD/m
Billed $96 USD annually
Class+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
30 Verified Answers

Related Documents

Related Questions