BPS 2110 Lecture Notes - Lecture 10: Nitroglycerin, Pharmacogenetics, Lipophilicity
7 Nov 2017
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De ne concepts from the provided list of important concepts. Distinguish the concepts of biopharmaceutics, pharmacokinetics, and pharmacodynamics. List ve factors that are susceptible to affect the drug concentration-time pro le. List the different information that can be derived from a drug concentration-time pro le. Anticipate the overall pro le of a concentration-time pro le for different routes of drug administration. Describe how drug bioavailability and drug therapeutic index can be experimentally assessed. List the different clinical applications of pharmacokinetic modelling. Drug concentration in blood is a good measure of the drug levels in surrounding tissues. Single-cell sub cellular pharmacokinetics: most drugs have to interact with a target receptor before its effects can be induced. Any substance or mixture of substances manufactured, sold, or represented for use in: The diagnosis, treatment, mitigation or prevention of a disease, disorder, abnormal physical state or the symptoms thereof: disease: due to an extrinsic factor, disorder: due to an intrinsic abnormality.
