BPS 2110 Lecture 6: bilogical target
3 Jan 2019
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Document Summary
Nucleic acid: linear chain of nucleotides. Polysaccharides: linear chains of sugars, some are branched. Lipids: linear chains of acetate or propionate, chain is modified so the assembly units are hidden . Build out of monomers that can be rebuilt and built. Easily assemble complex structures using simple ones. Only need 1 enzyme system for each biomolecule type. All proteins in the bodyproteins made by ribosome: dna made by polymerase, reduces machinery needed in the body. Easily dis-assemble complex structures and regenerate parts for use: protein disassembled by a proteasome. Proteins are most common target: nucleic acids less common. Have well defined 3 dimensional shapes: always chiral. Contact is required for biological reactions to occur. Drugs produce effects by binding to biological molecles. 20 different canonical amino acid types are used: occasionally some proteins contained unusual amino acids. Amino acids share same backbone and stereochemistry along the peptide bond.
