HSS 3106 Lecture Notes - Lecture 14: Peripheral Edema, Inotrope, Amrinone
5 Apr 2017
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Lecture 14 drugs and the cardiovascular system part 2. Blood pressure (bp): created by pumping action of heart; in arteries, bp rises during ventricular systole and falls during ventricular diastole. Cardiac output: volume of blood pumped per minute (determined by heart rate and stroke volume) Stroke volume: amount of blood pumped by ventricle in one contraction. Peripheral resistance: friction in arteries as blood flows through. Blood volume: amount of blood in vascular system. Used to treat mild, moderate and severe hypertension. Used alone or in combination with other antihypertensive agents, especially thiazide diuretics. Beta blockers primarily block b1 and b2 receptors. Reduce blood pressure by dilating blood vessels. May constrict air passages by stimulating the muscles that surround the air passages to contract. Non-selective beta blockers, such as propranolol (inderal), block b1 and b2 receptors and, therefore, affect the heart, blood vessels, and air passages.
