HSS 1100 Lecture Notes - Lecture 5: Levofloxacin, Bacilli, Exotoxin

• School: University of Ottawa
• Department: Health Sciences
• Course: HSS 1100
• Professor: Franco Pagotto

Document Summary

Gram-positive bacilli (rods); they are died purple love the purple shit. Spores are very stable, resistant to heat, drying, uv and disinfectants; spores germinate and toxins are made. Humans exposed to spores usually through contact with animals or soil. Used in bio-terrorism and warfare: bacillus anthracis exotoxin. Plasmid contains virulence factors which are transcribed optimally @ Where are, these conditions found: usually in lungs. Separately proteins are not toxic, but combined are lethal. Does(cid:374)(cid:859)t work agai(cid:374)st spore; (cid:271)ut yes, against vegetation. Capsule protects and it made of protein. Cutaneous and respiratory routes for spores (from inhalation or cuts on: bacillus cereus skin from animal/soil) Causes food poisoning when spores enter food product. Enterotoxin (something that affects gi tract) is responsible for illness. Heat stable: severe nausea and vomiting, short incubation. Clostridium: anaerobic differentiates this bacterium from other spore-forming bacilli, botulism, tetanus, gas gangrene and pseudomembranous colitis, powerful exotoxins rapid diagnosis, clostridium botulinum. Rapidly fatal food poisoning from lethal neurotoxin.