HSS 1100 Lecture 4: Lecture 9 notes
6 Jun 2018
School
Department
Course
Professor
Microbiology and Immunology
Notes: Lecture 9
Prof: F. Pagotto
Review
➢ Never give aspirin to a child who has chickenpox eause the a get Ree’s sdroe
➢ H1N1 means influenza, H stands for hemagglutinin and N stands for
neurogluttamine***
➢ What types of viruses
o Respiratory viruses
▪ Influenza (parainfluenza 5>, RSV 2>)
▪ Rhinovirus (common cold, no cross immunity)
▪ Adenivirus
o Enteric viruses
▪ Think about GI tract, rarely cause gastroenteritis
▪ Polioviris (Salk = immunocompromised, Sabin for everyone)
▪ Coxsackie (aseptic meningitis)
▪ Echo virus
o Viruses of diarrhea
▪ Rotavirus (vaccine >18)
▪ Norovirus (no vaccine 18+)
o Viruses of the rashes
▪ Measles (German measles can cause birth defects; measles causes rash
behind the ears)
▪ Varicella (causes chicken pox)
▪ HSV (1: causes cold sores 2: genital herpes)
▪ Papilloma virus (warts on hands and feet and can cause cervical cancer &
genital warts)
➢ Viral Life cycle
o Adsorption, penetration, nucleic acid & protein synthesis, assembly and
maturation, release
➢ Detection
o Direct visualization, cell culture (cytopathic effects, immunofluorescence,
hemagglutination), ELIZA
o Indirect detection (patient immune response)
▪ Immunity test
▪ Diagnostic test
➢ Viruses causing glandular enlargement
o Mumps
▪ Bilateral inflammation of parotid glands
▪ Lots of complications
▪ Through respiratory or ingestion
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HSS 1100 Full Course Notes
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Document Summary
Never give aspirin to a child who has chickenpox (cid:271)e(cid:272)ause the(cid:455) (cid:272)a(cid:374) get re(cid:455)e"s s(cid:455)(cid:374)dro(cid:373)e. H1n1 means influenza, h stands for hemagglutinin and n stands for neurogluttamine*** What types of viruses: respiratory viruses. Viral life cycle: adsorption, penetration, nucleic acid & protein synthesis, assembly and maturation, release. Detection: direct visualization, cell culture (cytopathic effects, immunofluorescence, hemagglutination), eliza. Viruses causing glandular enlargement: mumps, bilateral inflammation of parotid glands, lots of complications, through respiratory or ingestion, vaccine, problem is that there are sometimes no symptoms, occurs a lot in university symptoms. Infectious mononucleosis: transmitted by saliva, affects lymph nodes, can be chronic, detected by monospot test it detects rbc agglutination, use direct eliza, cytomegalovirus (cmv, we need to know the cmv status of transplant patients. If someone is cmv negative and someone is cmv positive and they transplant there will be an infection.
