HSS 2305 Lecture Notes - Lecture 18: Atp Synthase, Peroxisome, Organelle

• School: University of Ottawa
• Department: Health Sciences
• Course: HSS 2305
• Professor: Francois Cossette

Document Summary

5. 3 role of anaerobic and aerobic metabolism in exercise. 5. 4 oxidative phosphorylation in the formation of atp. 5. 11 diseases that result from abnormal mitochondrial or peroxisomal function. Mitochondrion structure: double membrane organelle with an intermediate space, outer membrane. Mitochondria tend to be more elongated and interconnected. Integral proteins having a large internal channel surrounded by beta strands. When wide open: atp, nad and coenzymes a can get inside the mitochondrion. Permeable due to porins: 2) inner membrane (high protein/lipid ratio; relatively impermeable, subdivided into two major domains that have different protein residents and carry out different functions: Lies just inside the outer membrane forming the double-membrane envelop. Rich in proteins responsible for the import of mitochondrial proteins. The other domain: present as a series of invaginated membranous sheets, called cristae. Responsible for the major role of the mitochondrion as energy transducer. Responsible for the high membrane surface required which houses the machinery needed for aerobic respiration and atp production.