NSG 3105 Lecture Notes - Lecture 5: Vertebral Compression Fracture, Metabolic Bone Disease, Hip Fracture
12 Apr 2020
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Document Summary
Chronic, progressive metabolic bone disease that can strike at any age but affects 1 in 4. Canadian women and 1 in 8 men over 50yo. Characterized by low bone mass (osteopenia) and structural deterioration of bone tissue. Increased bone fragility particularly of the hip, spine and wrist. Associated risk factors include european or asian decent, insufficient ca, cigarette smoking, alcoholism, sedentary lifestyle, low testosterone, menopause in women, oophorectomy. C for collapse: osteoblasts: cells that form new bone. For build: pth: regulates serum calcium through bone reabsorption. Leads to bone calcium loss and an increase in serum ca: estrogen: inhibits bone reabsorption. Women often have an increased risk due to rapid loss in perimenopause and lay lose as much as 15% of their bone mass with 3-4yrs: testosterone: increases levels of growth hormone (gh). Increases bone density and tells bone marrow to make. Low testosterone makes men more likely to suffer from bone fractures and breaks.
