PSY 2301 Lecture Notes - Lecture 13: Functional Magnetic Resonance Imaging, Multiple Sclerosis, Magnetic Resonance Imaging
Document Summary
Injure brain test behaviour to see what brain regions are important: many additional manipulations possible diet, social interaction, exercise, stimulate brain test behaviour, make animal models of neurological & psychiatric disorders stroke, Parkinson"s disease, dementia, etc. etc. & drugs: lashley (1920s-1950s) looking for site of memory lots of lesion studies, scoville & milner (1957) with no success. Brain lesions: temporal lobe surgery for epilepsy in a single patient (hm, bilateral removal of hippocampus, result amnesia; no new memories formed, eventually methods developed for making lesions of subcortical sites (e. g. hippocampus and midbrain) Brain stimulation: electrically or chemically (to enhance or block activity, wilder penfield (first director of montreal neurological institute at mcgill. Drug manipulations: drugs can influence specific neurons, we can study drug effects on behaviour and on new learning of a behaviour, e. g. Stimulants (e. g. amphetamine, cocaine, nicotine) can have long-term effects on plasticity.