BIOA01H3 Lecture Notes - Lecture 3: Genetic Drift, Mutation, Population Bottleneck

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BIOA01H3 Full Course Notes
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Lecture 3: hardy-weinberg and the agents of microevolution. Can assess observable phenotypic variation (when phenotype = genotype) Can measure genetic variation directly when phenotype does not equal genotype. In the past 15 years, commonly able to measure dna sequence more sequencers. Many cheap/high-throughput methods, based on the polymerase chain reaction (pcr) Collect fruit ies, crush them to release proteins, ll each well with sample from one y. Electric current passed through gel proteins migrate toward the + side according to charge and size (larger ones move slower) Ies have adh gene (alcohol dehydrogenase) which has 2 states - long and short. Gel is stained to produce color in the presence of adh enzyme to illuminate the proteins. Populations are made up of individuals of the same species, each with its own genotype. For evolution to occur, individuals within a population must differ genetically but not all populations are evolving.