BIOA01H3 Lecture Notes - Lecture 7: Autocrine Signalling, Intracellular Receptor, Growth Factor

• School: UTSC
• Department: Biological Sciences
• Course: BIOA01H3
• Professor: Aarti Ashok

Document Summary

Cells can communicate over long and short distances, environment affects behavior (send receive and respond to signals) Signaling molecules bind to and activate cell-surface and intracellular receptors, key to communication between cells and tissues (multicellular organisms) All organisms from prokaryotes to eukaryotes, single to multicellular require signaling for communication, signals may come from the environment or other cells. G protein-coupled receptors are a large, conserved family of receptors that often lead to short-term responses, receptor kinases are widespread and often lead to long-term responses. Specific signaling systems for both long and short communications, environment they find themselves in can affect. 2 major groups: g-proteins (specifically interact w/ g-proteins found in eukaryotic cells) and receptor kinases (take signal on outside, phosphorylates proteins on inside) Bacteria can talk to others and themselves secrete a molecule defined in euk are autocrine, in bacteria based on cell structure.