BIOA01H3 Lecture Notes - Lecture 24: Mitosis, Tumor Suppressor Gene, Carcinogenesis

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14 Aug 2018
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BIOA01H3 Full Course Notes
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Virus life cycles: bacteriophage (virus that infects bacteria) (lytic) Usually the trigger for lysogenic to turn into lytic is nutrients outside, other bacteria, etc. It relies on endocytosis to get into the cell. Virus life cycles: enveloped virus (hiv or zika virus) Hiv contacts the cell via receptors and co-receptors triggering fusion of its lipid bilayer with the cell and internal capsid is released to cytosol of the cell. Zika allows the cell to go through endocytosis and put it into a vesicle first, fusion occurs at vesicle le(cid:448)el. It"s lipid (cid:373)e(cid:373)(cid:271)ra(cid:374)e fuses with the endosomal membrane. Causing the capsid to be released into the cytosol. Non-enveloped only have one choice; to be endocytosed and released into the cytosol. Viruses can spread through direct or indirect contact. ~20%* of all human cancers = viruses contribute to their development. Ca(cid:374)(cid:272)er results due to a host"s respo(cid:374)se to the (cid:448)iral i(cid:374)fe(cid:272)tio(cid:374) or i(cid:373)pa(cid:272)t of (cid:448)iral ge(cid:374)es o(cid:374) the host (cid:272)ell.

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