BIOB10H3 Lecture Notes - Lecture 9: Intermediate Filament, Tubulin, Centrosome
24 Sep 2017
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Document Summary
The fluid of space that keeps the organelles suspended. Cytoskeleton proteins are present in there and various things. No signal for proteins to go to cytosol, are translated on free ribosomes, they stay there cause no signal to take them anywhere else. Proteins end up on cytosol through erad that has a proteasome which has a giant protease to degrade unfolded protein. In a neuron, a lot of strucutal support comes from light blue mircrotubes and dark blue which is intermediate filaments. Also spatial arrangement that seperates the two daughter cells are from actin and the movement of spindle from microtubles. Cytoskeleton elements are arranged on different sides aka apical sides ad basal lamnia sides: peroxisomes associate with microtubles to be positioned within the cytosol, hollow tubular structures found in eurkaryotic cells are called tubulin dimer. Building blocks of long polymer known as protofilament=head to tail: protofilament has polarity, beta is plus end and alpha is negeative end.
