BIOB51H3 Lecture Notes - Lecture 7: Mutation Rate, Genetic Variation, Tas2R38

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The variation is increased in offspring due to recombination and mutation. As variation continues, if selection is consistent in one direction, in every generation you can move up in terms of trait value. The change in trait value over generations required 3 things: selection, phenotypic variation, heritability, sources of phenotypic variation. If all phenotypes are identical, there can be no evolutionary change. Natural selection is expected to reduce heritable variation in populations Historical view: natural selection eliminates most variation, little variation present in current populations (evolution is a thing of the past!) But we now know that mutation is constantly generating new variants. Internal & external environment important for development of most traits. The expression of genes can be affected by the expression of other genes. These genes can produce their own protein that may be required to interact with the protein of the first gene to produce the phenotype.

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