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BIOC15H3 Lecture Notes - Lecture 2: Anemia, Mendelian Inheritance, Hh Blood Group

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corallocust714
9 Mar 2021
School
UTSC
Department
Biological Sciences
Course
BIOC15H3
Professor
Clare Hasenkampf

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Document Summary

Mendel"s laws in humans and extensions to mendel"s laws. Do humans follow mendelian inheritance: many heritable traits in humans are caused by interaction of multiple genes and thus don"t show simple mendelian inheritance patterns. Indicated by a vertical pattern of inheritance: every affected person has at least one affected parent, mating between affected and unaffected is effectively a testcross . A rare recessive trait: parents of affected individuals are unaffected but are heterozygous (carriers) for the recessive allele, show horizontal pattern of inheritance. Dominance is not always complete: the phenotype of the heterozygote defines the dominance relationship of two alleles, complete dominance: Hybrid resembles neither parent: codominance: hybrid shows traits from both parents. 2: 2 pink (r, 1 white (r. R: phenotype ratios reflect the genotype ratios. Abo blood types determined by 3 alleles: multiple alleles exist but each individual can carry only two, six genotypes but four phenotypes allele a type sugar.

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Related Questions

The inheritance rule was initially discovered by Mendel and it depends on clear or qualitative traits. The theory was based on a single gene that was responsible for one character. However, expression of many traits are not governed by a single gene, rather can involve multiple genes as well as additive effects. This kind of inheritance pattern is known as quantitative and is demonstrated by East (1916) as well as others. He performed experiments using 2 homozygous, pure-breeding lines of Nicotiana longiflora that differed in corolla length. After crossing these lines, F1 offspring had an intermediate length for corolla and had same variation level as in parents. But found a very different result for F2 and F3 than expected. Discuss the reasons for this result and if it agrees/disagrees with MendelĆ¢Ā€Ā™s law. Using obtained knowledge so far, what kind of cumulative effects would you add to this variation?

The inheritance rule was initially discovered by Mendel and it depends on clear or qualitative traits. The theory was based on a single gene that was responsible for one character. However, expression of many traits are not governed by a single gene, rather can involve multiple genes as well as additive effects. This kind of inheritance pattern is known as quantitative and is demonstrated by East (1916) as well as others. He performed experiments using 2 homozygous, pure-breeding lines of Nicotiana longiflora that differed in corolla length. After crossing these lines, F1 offspring had an intermediate length for corolla and had same variation level as in parents. But found a very different result for F2 and F3 than expected. Discuss the reasons for this result and if it agrees/disagrees with MendelĆ¢Ā€Ā™s law. Using obtained knowledge so far, what kind of cumulative effects would you add to this variation?

The inheritance rule was initially discovered by Mendel and it depends on clear or qualitative traits. The theory was based on a single gene that was responsible for one character. However, expression of many traits are not governed by a single gene, rather can involve multiple genes as well as additive effects. This kind of inheritance pattern is known as quantitative and is demonstrated by East (1916) as well as others. He performed experiments using 2 homozygous, pure-breeding lines of Nicotiana longiflora that differed in corolla length. After crossing these lines, F1 offspring had an intermediate length for corolla and had same variation level as in parents. But found a very different result for F2 and F3 than expected. Discuss the reasons for this result and if it agrees/disagrees with MendelĆ¢Ā€Ā™s law. Using obtained knowledge so far, what kind of cumulative effects would you add to this variation?