BIOC32H3 Lecture Notes - Lecture 3: Extracellular Fluid, Myelin, Resting Potential

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3:54 pm http://www. st-andrews. ac. uk/~wjh/neurotut/mempot. html --> link to online tutorial about membrane potential. Opening and closing of v-gated ion channels cause changes in membrane permeability. Leads to changes in the excitability of the cell. In excitable cells, vm changes in response to voltage. Changes in membrane potential are known as membrane potential difference. Depolarization occurs when vm is positive --> the cell becomes less negative. Hyperpolarization occurs when vm is negative --> cell becomes more. Hyperpolarization occurs when vm is negative --> cell becomes more negative. Repolarization occurs when vm becomes negative after it has been depolarized. The cell returns to its original membrane potential. Changes in membrane potential happen quickly and do not always result in an action potential. Localized close to the cell membrane that it only effects relatively small area. The ic and ec has a pretty stable composition. Depolarization mainly due to the activity of na channels. Both gates are never closed at the same time.

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