BIOC32H3 Lecture Notes - Lecture 4: Giant Cell, Multiple Sclerosis, Backpropagation
18 Sep 2017
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Depolarization due to na channels opening causing the opening of more na and k channels. Positive feedback loop allows conduction of ap down the axon. Absolute refractory period where no amount of stimulus can create a 2nd action potential in the cell. Due to resetting of na gates into their default rmp settings. Relative refractory period where a larger than normal gp required to create ap. Some of na have reset but not all. Refractory periods stop the action potential from travelling backwards, up the axon. The circles diagram shows part of where refractory period starts as na can no longer move through the channel longer move through the channel. Cell body of neurons integrate various graded potentials. The higher the amplitude, the greater the potential. Gp have an additive effect --> 2 gp occurring closely in time and spot result in combined gp. Action potentials do not summate --> amplitude does not change.
