BIOC32H3 Lecture Notes - Lecture 21: Epiphyseal Plate, Diaphysis, Chondrocyte
Document Summary
Calcium: storage in the body and function: calcium important for physiological function of bodies. Intercellular cement between cells cell adhesion: cofactor in blood coagulation cascade (wont talk about this at all, plasma ca2+ affects excitability of neurons muscle contraction, some people regard calcium as a hormone. Blood [ca2+] is closely regulated: very closely regulated, calcium is controlled by how much we eat and the hormones that regulate it, ca intake. Ingested in diet: absorbed in small intestine only 1/3, hormonally regulated, ca output mainly through kidneys. Increases ca by breaking down calcium crystals in bone: enhances kindey reabsorption of ca. Increases intestinal absorption of ca via calcitriol (vit d3: lack of pth is lethal death. Ca levels not crucial for life (have other ways of compensating. Regulation of ca levels: pth and calcitriol increases plasma ca, calcitonin decreases plasma ca, summary of mechanisms.
