BIOC34H3 Lecture Notes - Lecture 18: Nephron, Cholecalciferol, Homeostasis

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29 May 2019
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Lecture 18: calcium regulation, glucose regulation and clearance: calcium regulation, calcium levels in blood are regulated by hormones. Calcium exchange occurs between the blood and is stored in bone, gut and kidney: absorb calcium from digested food in gut or reabsorb it from kidney. Rates of absorption from gut or reabsorption from kidneys can be regulated depending on whether plasma calcium levels are high or low. Calcium from bones can be added to blood or deposited back into bone. Calcium removal from bone is resorption whereas calcium deposit into bones is calcification or deposition: 3 primary hormones: parathyroid hormone, calcitrol (both involved in raising plasma calcium), and calcitonin (involved in lowering plasma calcium). Parathyroid hormone and calcitonin made in parathyroid and thyroid glands: calcitonin is produced by thyroid gland in response to high ca2+ in blood plasma. Pth also stimulates production of calcitrol which causes calcium uptake from gut to increase: calcitrol produced when plasma calcium levels are low.

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