BIOC39H3 Lecture Notes - Lecture 1: Fowl Cholera, Myasthenia Gravis, Innate Immune System
Document Summary
The etiology, pathogenesis, and clinical manifestations of many diseases are rooted in the immune response. Systemic lupus erythematosus a disease that can affect any tissue of the body b cells and produce antibodies. Transplanting tissue during world war; response to foreign tissue causes this kind of disease. Cancer immunotherapy used to attack those tumor cells. Therapeutic antibodies are the highest earning category of biological drug some 30 approved antibodies, hundreds more in development and testing. Treat(cid:373)e(cid:374)t of se(cid:448)eral (cid:373)ajor diseases i(cid:374)(cid:272)ludi(cid:374)g autoi(cid:373)(cid:373)u(cid:374)e, cardiovascular and infectious diseases, cancer and inflammation. Immune system the tissue, cells, and molecules mediating defense of the body against infectious agents. Immunization the deliberate provocation of an immune response. Idea of (cid:858)i(cid:373)(cid:373)u(cid:374)it(cid:455)(cid:859) re(cid:272)og(cid:374)ized i(cid:374) a(cid:374)(cid:272)ie(cid:374)t so(cid:272)ieties -450 dc; during plague, people who got disease and recovered were immune to infection. Kach 1880; described germ theory of disease infectious mo are root cause of the disease; demonstrated by pasteur (development of vaccine)
