EESA10H3 Lecture Notes - Lecture 4: Bisphenol A, Hypospadias, Carcinogen
26 Jan 2017
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Document Summary
Contaminants are any chemicals that may or may have adverse human impact but not necessarily cause health impact. Bioaccumulation accumulate in the body (hair, nails) in the same individual build up concentration in tissues, Bio magnification- individual build up but in the food chain the animal at the top will have the highest concentration. Endocrine disrupters- data mostly from animal studies not much from human exposure. Changes in the level of produced proteins: indirect effects: Synthetic estrogen used by physicians to prevent spontaneous abortion (1948-1971) Administered for early pregnancy until 35 weeks. >1 million women took it between 1960-1970. Daughters whose mothers took des have increased incidents of: reproductive organ dysfunction, abnormal pregnancies, reduction in fertility immune system disorders, carcinoma. Thyroid dysfunction- function is to produce hormones t2 t1 are regulated by production and that hormone is produced by pituitary gland and that hormone tell thyroid when in high and low concentration.
