EESA10H3 Lecture Notes - Lecture 10: Reference Dose, Risk Assessment, Canada Council
16 Oct 2017
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Risk assessment: what is the risk, risk = probability of suffering harm from a hazard, risk paradigm. Problem definition: purpose which contaminant do you want to evaluate, management goals, policy context who"s conducting assessment, receptors , audience, hazard definition, level of funding, 2. Identify contaminant: single compounds or, complex mixture with a few compounds driving toxicity, contaminated soil, and/or air pollution and/or ? of the chemical, this will be decided based on the physical-chemical properties, 3. Pathways analyses: determine environmental fate that results in exposure to receptor, evaluate routes of exposure, quantify amount of exposure (dose, methods, measurements (how representative is the sample measurement?, modeling, 5. Toxicity and risk assessment: noncancer effects have thresholds, carcinogenicity has no threshold, therefore, key steps in risk assessment play out differently for cancer, assessment of non-carcinogenic hazard one as basis, 3. Dose-response assessment (no threshold) and non cancer (threshold) effects: 1.
