EESA10H3 Lecture Notes - Lecture 9: Lead Paint, Aspirin, Vitamin A

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Common sources of lead exposure old pipes and soil. It is hard to evaluate the effect of chemical because people have different sensitivities. Determination of severity of adverse effects: the properties of the chemical: potency of the chemical, sensitivity to that particular chemical, how much enters the body length of exposure. Basic concept of toxicology: the dose makes the poison , developed nearly 400 years ago by a well-known physician known as paracelsus, toxicologists adopted this model, eg. If you take a fraction of a dose of aspirin, it isn"t going to really do a lot to your system. If you have a headache and take several aspirins, it will probably alleviate your headache. It commonly occurs in vegetables, fruits, and fish. It can be formed from beta-carotene an orange material that gives the orange color to squash and carrots. Vitamin a or retinol is essential but high doses cause central nervous system damage particularly in children.

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