EESA10H3 Lecture 9: information from lecture slides + information added by prof during lecture

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14 Apr 2011
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Toxicology is the study of poisons from all sources (air, water, food, etc. ) Poison substance that causes harm and leads to harmful effects. Not all chemicals cause the same level of harm, how harmful a substance is depends on the chemical properties of the substance (electronegativity, polarity, oxidation state, molecular weight, dissociation, solubility, etc. ) Receptor: the organism receiving the exposure or dose. Receptor characteristics (frequency of exposure, age, general health, genetic makeup) affect whether the receptor will develop the disease. Specific response: specific organs experience specific effect: damage to excretory/respiratory organs, damage to reproductive function, carcinogenesis. Acute toxicity: related to acute dose, in many cases: quick death. Chronic toxicity: could be symptoms that last for a long time. Every chemical is harmful at some level of exposure; every substance is poisonous, but at differing doses (i. e. 3l or more of pure water is harmful) A risk is the possibility or probability of suffering harm from a hazard.

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