o22 000 ppl signed up for pilot study in Hamilton, ON.
•Link identified by Dr. Roger MacIntyre
oInsulin places a big role in triggering mood disorders and metabolic
changes in the brain
oIllnesses such as depression and other affective disorders are being caused
Further research how insulin levels affect our moods
Prozac a few years ago was considered effective in treating
depression which is incorrect
Use of insulin nasal inhaler to treating symptoms of depression
Correlation between obesity, diabetes, and depression
•50-75% patients suffering from diabetes and depression are
obese or overweight
•Research is at an early age
•Example of adverse reactions: Montelukast sodium (Singulair), a leukotriene-
receptor antagonist prescribed for treatment of asthma in patients 2 years of age
• It is also indicated for the relief of symptoms of seasonal allergies in patients 15
years of age and older when other treatments are not effective or not tolerated.
Montelukast has been marketed in Canada since 1997.
•Eg. Prozac has been prescribed for weight loss and is an example of off-label drug
•Antibiotics and penicillin to treat infections and diseases
•Risks and adverse side effects related to drugs
•Most ppl are often health illiterate and are often embarrassed to ask
questions from their doctors and pharmacists
•Adverse reaction caused by singulair and treated allergies and
asthma to relieve symptoms related to seasonal allergies and dangerous for
kids under the age of 15
•Singulair was available to children as young as 12 mos.
•Between Sep 2007 and July 2008, updated with a
monograph to convey risks of depression and suicide
•FDA early communication reported possible link between
depression and suicide; reports increased 7-fold of linked cases
of singular and thoughts of suicide and development of