NROB60H3 Lecture Notes - Lecture 6: Resting Potential, Oscilloscope, Repolarization

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16 Aug 2020
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Lecture outline: the action potential, the ups and downs, in theory, in reality, conclusion. Once the action potential fires, it is no longer graded and the overshoot is the same! If current reaches threshold, generate action potentials will generate (at a low rate) Increase current and rate of ap generation increases. Optogenetics => controlling neural activity with light https://www. youtube. com/watch?v=i64x7vhshoe: novel technique, come about in the last 10 years or so (this video is 2010) The channel that causes algae to move away from light is light-activated channel. Potential applications of this kind of activation in the brain! Light activates neurons that makes the animal walk in circles => light controls the behaviour of cells (optogenetics). The action potential (in"s and out"s, in theory) Assume a theoretical neuron with no channels in open state. There"s more k+ inside relative to outside of the neuron. All we have done is change the membrane permeability towards.

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