PSYB64H3 Lecture Notes - Lecture 4: Drug Action, Neurotransmitter, Small Molecule
Document Summary
You are only responsible for the content covered in these lecture slides. Identifying neurotransmitters: must be synthesized within the neuron. In response to an action potential, the substance is released in sufficient quantities to produce an effect in the postsynaptic cell: we should be able to duplicate the action of a suspected neurotransmitter experimentally on a postsynaptic cell. Some mechanism exists that ends the interaction between the neurotransmitter and the postsynaptic cell. Drug" is reserved for things that have pronounced effects when ingested in small quantities. Examples of commonly used drugs and their effects. Agonists enhance the activity of a neurotransmitter. Antagonists reduce the activity of a neurotransmitter. Part 1 drug action at the synapse (pre) Neurotransmitter production: manipulating the synthesis of a neurotransmitter will affect the amount available for release. Interfering with the storage of a neurotransmitters in vesicles within a neuron.
