PSYB64H3 Lecture Notes - Selective Serotonin Reuptake Inhibitor, Gaba Receptor, Autonomic Nervous System
14 Jun 2013
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Drug actions at the synapse: agonists & antagonists, neurotransmitter production, storage & release. Note: lecture content is from chapter 4. You are only responsible for the content covered in these lecture slides. Basal forebrain projections to hippocampus and amygdala; the septum; the brainstem. Ventral tegmentum projections to hippocampus, amygdala, and nucleus accumbens. Ventral tegmentum projections to frontal lobe of the cortex. Pons (especially locus coeruleus, which projects widely to spinal cord and brain) Particularly the raphe nucleus, and project widely in the brain and spinal cord. Widely distributed in the central nervous system. Relaxes smooth muscle cells in blood vessels. Drug" is reserved for things that have pronounced effects when ingested in small quantities. Examples of commonly used drugs and their effects. Stimulates gaba receptors; acts as an antagonist at the nmda glutamate receptor; stimulates dopaminergic systems. Reduced anxiety; mild euphoria; loss of motor coordination. Agonists enhance the activity of a neurotransmitter. Antagonists reduce the activity of a neurotransmitter.
