PSYB65H3 Lecture Notes - Lecture 7: Alcohol Tolerance, Ice Cream, Hallucinogen
Document Summary
Transmitter systems: how they work, different aspects, relation to psychiatric disorders. Transmitter systems: variations of transmitter systems, how they affect human behavior. Drugs: impact on transmitter systems, stimulants, depressants, hallucinogens, opiates. Anything that you can use and ingest that impacts the human systems: how it affects human brain, how it affects human behavior. No value judgment: up to individual, up to society. Over the counter drugs: at the drugstore, no need for prescription. Concept that if a drug is taken repeatedly, then most drugs will exhibit a decreasing behavioral effect: more you take it, the less effect it has. Mechanism of tolerance: compensation of system by increasing or reducing sensitivity / number of receptors on postsynaptic neuron. Mechanism for most drugs: there are other mechanisms. Regardless of mechanism tolerance refers to decreased behavioral effect. Drugs that alter a transmitter system by: increasing packaging, increasing release, stopping reuptake, mimic neurotransmitter, mimic receptor.
