PSYB65H3 Lecture Notes - Lecture 5: Opioid Use Disorder, Methadone, Cyclic Adenosine Monophosphate
Document Summary
Psychopharmacology: study of how drugs affect the nervous system and behaviour (internal and external behaviour) Drugs: chemical compounds administered to produce a desired change in the body (whether for recreational or medical use) Psychoactive drug: substance that acts to alter mood, thought or behaviour and is used to manage neuropsychological illness. Drug action at synapses: most psychoactive drugs exert their effects by influencing synaptic chemical signaling, agonist substance that enhances the function of a synapse, antagonist substance that blocks/decreases the function of a synapse. In tolerance, a learned behavior results when a response to a stimulus weakens with repeated presentations; the intensity of a response decreases if been repeated. Metabolic tolerance: increase in number of enzymes used to break down substance (especially when that substance is toxic: ex. If you drink for the first time, there is a very strong effect; if you are used to it and ca(cid:374) tolerate alcohol, you (cid:449)ill feel less (cid:862)dru(cid:374)k(cid:863)
