PSYB32H3 Lecture 10: PSYB32 Lecture 10
Document Summary
Behavioural problem is due to abnormal activity in frontal lobe. Cortical basal degeneration results in alien hand syndrome, involuntary hand movement. Women with dementia in general tend to live longer but a higher chance to die from alzheimer"s disease. Men have higher chance to die from stroke. Risk factor is the e4 gene, early onset of alzheimer"s disease. Having two e4 genes, the prevalence is 90% Sequence of disability: memory (hippocampus), speaking (temporal), orientation problem (parietal) Tangles and plaques are present in normal people"s brain, the difference is the number of them, patients with alzheimer"s disease have more tangles and plaques. Risk factor: head injury, depression, cognitive reserve. Notion that high education level delays clinical expression of dementia because brain develops back up reserve/ neuro structure as a form of neuro plasticity. Cognitive activity preserves cognitive function (use it or lose it) Cognitive activity gets better with crystallized intelligence but not with fluid intelligence.
