BIO120H1 Lecture 10: Lecture 10
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BIO120H1 Full Course Notes
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Lecture 10: cell communication through signaling, unicellular organisms. Example: regulation of cell movement: slime mold (unicellular) attracted to camp chemotaxis moves toward high concentration of chemical. signal for single cells to aggregate to form slug: micropipette with camp. movement by extending a new pseudopod: signal molecules and receptors, 1) cell surface receptors. bind to hydrophilic ligand: 2) intracellular receptors. transported by carrier proteins in extracellular fluid and deliver to cells. because not soluble: classes of cell surface receptors in animals, 1) ion-channel-linked receptors (ligand gated ion channels) Regulated by neurotransmitters: 2) g-protein-linked receptors (gpcr) receptors to visual, taste, smell, and many other neurotransmitters: 3) enzyme-linked receptors www. notesolution. com. cytosolic domain has enzymatic activity or is associated with an enzyme. examples: receptor tyrosine kinases (rtks, tgfb receptor serine/threonine kinases, cytokine receptors (jak/stat pathway, 4) other receptors. *transmembrane domains; include protein degradation to activate pathway: cell surface receptors in plants, enzyme-linked receptors:
