BIO120H1 Lecture Notes - Lecture 5: Genetic Drift, Zygosity, Genetic Variation

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19 Jan 2016
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BIO120H1 Full Course Notes
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BIO120H1 Full Course Notes
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P = proportion of genes that we sample in a population. There are more than one type of alleles. Fraction of genes that we sample, but a variable. Everybody might have the same gene, and that is not polymorphic. We have to measure it by taking sample from a large population. H = how many of the genes are present in one individual that are heterozygous then average for the population. It gives us a measure of how many heterozygous genes an average individual have. Mutation (increase): brings in variability and caused by random errors during replication of the dna. We can lose variability in a population through random genetic drift (decrease). This is a force that reduces genetic variability as a result of small population size. Natural selection (increase or decrease depending of the selection): takes away variability if it is bad. Positive selection when a good mutation spreads because it increases fitness.

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