BIO130H1 Lecture Notes - Lecture 12: Peroxisome, Endomembrane System, Protein Targeting

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10 Oct 2016
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BIO130H1 Full Course Notes
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A subcellular compartment or large macromolecular complex, often membrane-enclosed, that has a distinct structure, composition, and function. Examples of membrane-enclosed organelles: nucleus, endoplasmic reticulum, golgi apparatus. Examples of organelles that are not membrane-bound: nucleolus and centrosomes (important role in organizing cytoskeleton) Example of polarized cell with apical domain (microvilli) that looks different from the basal domain (flat) Relative amounts of membrane types in two kinds of eukaryotic cells. Plasma membrane makes up quite a small portion of the cellular membrane. Part of what allows the cell to perform different functions. Cells can also change the amount of organelles inside as well; when drugs are constantly being degraded in the liver, an increase in smooth er allows for a higher amount of detoxification to cope with those drugs. All function together in a specific pathway. Include er, golgi apparatus, lysosome/vacuole (in plants), peroxisome: biosyntehtic/secretory pathways secretion, secreted proteins, contents move out of the cell (exocytosis)

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