BIO130H1 Lecture Notes - Lecture 3: Secretion, Integral Membrane Protein, Endoplasmic Reticulum
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BIO130H1 Full Course Notes
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Chapter 8: p270 275, 279 294, 303 308, 316 318. Volume will be different in different cells! Protein synthesis and degradation of various compounds intermediary metabolism (degradation and synthesis of small molecules) Definition: a subcellular compartment or large macromolecular complex, often membrane enclosed, that has a distinct structure, composition, and function. Examples organelles that are not membrane bound: Rer: rough endoplasmic reticulum synthesis of transmembrane, organellar and secreted proteins. Ser: smooth endoplasmic reticulum phospholipid synthesis, detoxification. Note: ribosome, polyribosome not considered as organelles! More membrane in the cell than around the cell (also thicker) Inside the cell, there are a lot more membrane bound organelles. Pancreatic exocrine: secrete a lot of digestive enzymes. Together these organelles form the: endomembrane system. Indicated by red circle: rer, golgi complex, lysosome, endosome. Proteins and lipids made in the er delivered to the membranes of other organelles. Contents move out of the cell (exocytosis) Contents move into the cell (endocytosis )
