BIO120H1 Lecture Notes - Lecture 18: Ptk2, Cell Membrane, Intermediate Filament

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2 Feb 2013
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BIO120H1 Full Course Notes
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BIO120H1 Full Course Notes
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We ended last day talking about collagen, which is one of four types of fibrous proteins, so now we"ll talk about these other three. These fibrous proteins run through the extracellular matrix providing structural support similar to how cables would run through reinforced concrete. We learned how collagen could form these long bundled structures running through tissues, but collagen, its organization can vary with tissue type. You can imagine that for example in a tendon, you may want a whole bunch of collagen fibres to be in parallel to form that tendon structure. Underlying our skin however where it is more of a plane, you would want more of a meshwork of criss-crossed collagen molecules to support our skin. Different tissues call for different organization of collagen and the organization of fibrous collagen is regulated in large part by these fibril associated collagens so there are different types listed.

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