BIO130H1 Lecture 7: Lecture 7
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BIO130H1 Full Course Notes
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Lecture 7: transcription 1: molecular definition of a gene, transcription and rna polymerase in prokaryotes. Molecular definition of a gene o o. Invokes the whole idea of coded information and turning it into something that the cell can use. The entire nucleic acid sequence (usually dna) that is necessary for the synthesis of a protein (and its variants) or rna. In other words, genes are segments of dna that are transcribed into rna. Transcription is a controlled mechanism which is used to modify patterns of expression it allows the cell to determine what level of expression is going to occur for that encoded information. It must be transcribed in one of the strands in 5" to 3". 5 in total because there"s the newly duplicated subunit. Catalyzes the sequential addition of nucleotides o o o o o. Rna nucleotides are linked by phosphodiester bonds through ribose phosphate backbones.
