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BIO220 Lec 1

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Jennifer Harris

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Lecture1 Tuesday,September 13, 2011 8:55 PM Chapter 1, Pg. 1-8, 14-16; Chapter 4, Pg. 411-416, 432-438 Liveinextremeenvironments Eubacteriaonly Procaryotes • Eubacteriaandarchaea • Smallsimplecells • Liveindependentlyorinlooselyorganizedcommunities(notmulti-cellular) ○ Arealannoyanceinhospitals • Lacknucleusandorganelles Collera Notallhaveflagella Nucleoid Screen clipping taken: 9/13/2011, 12:39 PM Eukaryoticcells • Plants,fungi,animals,humans • Canbesingled-celledormulticellular • Presenceofnucleiandorganelles • Muchlarger Animalcell Animalcell Screen clipping taken: 9/13/2011, 12:42 PM • Plantshavecellwalls ○ Alsochloroplasts Genomes • Allknownlifeformspossessgenome ○ Encodesinformationtoconstructandmaintainorganism • MostlyDNA ○ VirusessometimeshaveRNA • Releaseofbiologicalinformationingenomerequiresgenomeexpression Genomeexpression 1. TheTranscriptome DNAmicroarray: Redismoreexpression(moreRNA) Greenislessexpression(lessRNA) Eachcellexpressesdifferentpartsofgenome Screen clipping taken: 9/13/2011, 12:54 PM ○ Transcription  WhenRNApolymerasetranscribesDNAintomRNA 2. Proteome ○ Collectionofproteinsinacell ○ Definesthebiochemicalfunctionsofcell Rediscommonproteins
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