CSB351Y1 Lecture 20: Lecture 20
15 Feb 2012
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Pre-class pep talk: don"t phone me, don"t email, drop by in person, term test 1 related talk etc. I went a bit through the cycle (last class). A diagram of it (referring to previous lecture). Glycoprotein means protein has sugar attached to it. Because, agglutinate means attach, hemagglutinin means red blood cells. So this hemagglutinin has a property, it"s a glycoprotein of the virus, which if you put it to red blood cells it agglutinates the red blood cells. That"s why they call it hemagglutinin, originally it"s a historical name. The function of this hemagglutinin is to bind on the surface of cells to sialic acid. Sialic acid is a very common molecule on the surface of cell in upper and lower respiratory tract. So allow virus to attach to the cell and you have receptor- mediated endocytosis and the virus gets in. It"s a glycoprotein coded for by the virus.
