CSB328H1 Lecture Notes - Lecture 6: Neural Tube, Gastrulation, Notochord
Document Summary
Mechanism that allows the embryo to become more and more complex (ie. more cell types) Inducer cells and cells that are competent to respond. Certain potential and certain limitations at each stage. Neural ectoderm can only be formed at a certain stage of development. Heterotropic transplantation of dorsal blastopore lip from an early gastrula into the ventral side of the host embryo (more complicated because it isn"t just being dropped into the blastocoel) Used 2 different newt cells ; one pigmented and one not pigmented. Normally mid gastrula we have the formation of the dorsal blastopore lip. This first involution is followed by a secondary involution (simultaneously) on the ventral side (where the grafted tissue was transplanted) Dorsal side: had neural tube, somites, notochord, lumen of gut (normal) Ventral side: had the same structures on this side! Grafted tissue formed mostly notochord, some neural tube, and a little bit to somatic tissue.
